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Heres a case of a 67-year-old man who reacted to a hydroxocobalamin B12 shot containing 1.5% benzyl alcohol

By activating transcription factors like NF-B and activator protein 1 (AP-1) and upregulating kinases like phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinases (MAPKs), ROS generation can cause pro-inflammatory responses (Chen and Kunsch 2004)

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